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A phrase used to describe the act of being or getting "fucked up". It is a versatile term that can be shouted out loud to show enthusiasm towards getting "messed up" on whatever you prefer.
Examples:

1. Ya buddy lets get One Timed!
2. Those keg stands really got me One Timed!
3. Grab the Grav, I wanna get One Timed!
by FeedUsMcFetus August 28, 2010
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1.to get your ass rolled very quickly, usually in one punch.

2. jumping someone never to be seeing them again.
guy 1: Remember that time that Thomas one-timed his older broter.
guy 2: yeah after he dropped the x-box controller and then got mad at Thomas.
guy 1: yeah, Thomas totally one-timed his ass again.
by JOHN THOMAS CHRIS GRAHM. January 25, 2009
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