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(For dudes only) to hook up with a chick after just meeting her. also, to be able to charm the SHIT outta that chock to the point where she is under your thumb.
Man, me and Hobbs were at the bar last night, and he was just fuckin' lockin' 'em up!!!
by Zaggs June 22, 2005
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Jun 24 Word of the Day
An exclamation made when your friends or family are teasing you to a point where you can't handle it anymore and a hissy fit is in order.

Derived from a YouTube user's famed outburst following Britney's lackluster performance at the 2007 VMA's.
Sarah: 'OMG Susan, I can't believe you are wearing the same skirt as yesterday. Oh, and by the way, EVERYONE knows what you did with Kevin on the weekend. Plus you look a little fat, are you retaining water?'

Susan: 'LEAVE BRITNEY ALONE!'
by Billy Chickenhole September 15, 2007
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2
term used in the crack cocaine trade which refers to cocaine getting hard when cooked. When boiled cocaine oils rise to the surface of the water and then ice is added at which point the cocaine gets hard or "locks up"
I bought a kilo from that guy the other day and when I cooked it it wouldn't lock up.
by Lbs. May 30, 2008
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3
noun. Also known as a jail.
When you get arrested you get thrown in lock up
Dammmn. He's in lock up for 3 months cuz he stole from his friends house.
by britlin June 29, 2003
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4
The act of holding a dick in ones mouth while the person sits on their shoulders. By sitting on the others shoulders and inserting their dick in the others mouth, it forms a "lock" between the two people for stability or other needed reasons.
I couldn't reach the jar on the top shelf so my girlfriend let me sit on her shoulders, then she let me lock-up so I didn't fall.
by Geoffy Geoff May 24, 2011
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5
A ridiculously bad 80's movie with Stallone. It's good for unintentional comedy.
Lock Up
http://www.youtube.com/watch?v=NEQbofU3maE
http://www.youtube.com/watch?v=jQ5TwKApFC4
by Leone510 April 28, 2009
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6
When you “Lock Up”, you remain calm in conflicting situations or you conceal your true intentions so as to avoid embarrassment, awkwardness and the likes. This is a Nigerian (Warri) slang.
#1. She was giving me an attitude so I locked up.
#2. As some guys enter the area dey looseguard I just lock up.
by jeZZZe February 25, 2019
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