ixie Share definition Flag A very good friend, a sisterly friend, a best friend, someone from yor clique. Also used as an exclamation you yell to your friends to get their attention. A Canadian word. Kristin is my ixie, she helped me with the killer math homework or HEY! MA IXIES! Wait up! ixie by Lena September 21, 2006 0 0 Get merch Get the ixie mug. Buy Now — $32.95 See more merch
