Top Definition
Hand Sanitizer
Yo bro, my hands are dirty. Pass me the hand sauce
by YoshiMaster620 November 05, 2017
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male ejaculate; semen

Can also be used as a verb
"Yo dawg, sorry I couldn't text you back, I was making hand sauce."

"We were playin' Rocket League the other night and were just hand saucing the fuck out of those nerds."
by Shrekkin' Nerds August 21, 2015
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The slowly-built-up brownish filth that accumulates on items that come in contact with many different dirty fingers. Commonly found on that nasty 10-year-old keyboard you have to use at work, public restrooms, remote controls, etc. Source: overheard in local conversation
"I ain't touchin that nasty-ass mouse of yours until you clean that hand sauce off of it"
by jake5443 March 06, 2006
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