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In other words, "darn it". Commonly used while swinging your arm in a fashion similar to one arm punching your opposite bicep.
Hey man! That guy took the last bag of Big League Chew. Gazooks!

Gazooks, I underestimated the amount of toilet paper left on the roll!
gazooks by rhinografix September 10, 2010
Related Words

gadzooks 

1.) A term of surprise uttered by JFK when he found out Kennedy aide Kenneth O'Donnell had received a watch from Marylin Monroe (see also Preston and Steve or WMMR)
2.) An ice cream concoction created by the members of the Preston and Steve Show, distributed by Bassett's Ice Cream
3.) An as-yet-uncreated cookie created by the Preston and Steve show (see also Gadzookie)
1.) "Did Jackie see it? Oh for Christ's sake tell me Jackie didn't see it! Holy crap! I don't care where you put it, pound it up your ass, but get it out of here! GADZOOKS! Yeah , Yeah, Cuba has missles, where's the watch?" - Steve Morrision
2.) "I went to WAWA and those clowns were out of Gadzooks! Ice Cream"
gadzooks by Sean McC. October 27, 2006

gadzooks 

A term used to signify alarm. Popularized by comics, used on the the 1960's Batman show.
Gadzooks boy wonder, these tights are straining me!
gadzooks by stinkoman February 24, 2004

gazookas 

Another term of big hooters.
tig 'o' bitties
Look at those huge gazookas!

gadzooks 

Gadzooks, it seems that somebody peed in my pants!
gadzooks by Acceleratedbeats December 12, 2003

Gadzooks 

A sacred word used to invoke a spiffy ratio building period on a particular torrent site.
User 1 : Man the seedboxes, there be a ratio building ahoy!Yarrrrrrr!

User 2: Gadzooks?

User 1: Gadzooks!!
Gadzooks by Sheeeeee-it October 26, 2010