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A gram negative rod-shaped bacteria that's a fecal contaminate. Also returns pornographic search results in Google.
That E Coli comes from poop.
E Coli by MrBlack13589 November 16, 2010

E-Coli conservatism

political belief in cutting government costs even if such cuts result in devastating harm.
We have E-Coli conservatism to thank for lead in children's toys, unsafe non-prescription drugs, and dangerous spinach.

E.coli does it better 

a smug statement used by biochemical engineers while in conversation with chemists, once this is said it will often cause a heated debate between the two scientists. this relates to the fact the the E.coli bacteria can be modifided to produce chemical compounds, stealing the job of chemists.
chemist: 'I'm designing a process to produce a new anti-A.I.Ds medication'
biochem engineer: 'You do know that E.coli does it better'
E.coli does it better by Bluntman DC February 14, 2009

E-coli cubes 

The innocuous appearing, yet horribly contaminated, foreign-water cubes of misery that wreak holy-fucking-hell on unsuspecting Traveller bowels.
So, I didn't actually DRINK the water, or eat ANYTHING washed in water ... it was the E-coli cubes that took me down; never again!
E-coli cubes by YAWA September 30, 2019

e-coli pie 

A slang term for one's asshole, or poop-chute, if you will.
Tom Cruise really loves to eat the e-coli pie
e-coli pie by KirstenTheWise April 22, 2006

E.coli Nigger 

nobody knows what this means but if you are called this under no circumstances should you accept it
E.coli Nigger by JamArtisan April 29, 2022