1. To be completely feed up with
something and not give a shit anymore.
2. Used to let someone know they are either drunk and shouldn't drink anymore, (2a)or they've dont
something wrong and are gonna get the shit kicked out of them.
1. I hate
art school, I'm donezo.
2. Dude, Josh is fighting a dog, he needs to go home he's donezo.
2a. Did you
just take my beer?!?! That's it, you're face is DONEZO!!!