An expression meaning that if one thing/person/etc. is affected in some way, all those surrounding it will do the same.
1. If one infected person sneezes in an elevator, most of the people inside will eventually become sick.
2.If the Soviets invade one of its neighbors, many others will succumb to the same result soon enough.
by Smkngmgc September 17, 2004
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The effect that Domino's pizza has on you abput 15 hours after you eat it.

domino's pizza company, as you may know, is a place to call when you're sitting around at 2:00 am (most likely intoxicated)starving to death.

However, your impulse decisions will eventually bring on the Domino's Effect within 15 hours or less. Signs of the Domino's effect are:
1) extreme amounts of gas, including farting and sulfuric acid/carbon dioxide belches.
2) trips to the restroom about 4 times per half an hour for anywhere from 2 - 9 hours.
3) green diarrhea and excretion of all consumed liquids (soda, water, beer, juice, etc.)
4) a slight comatose feeling

When you get the Domino's Effect, it's best to just wait it out. Don't make plans for the next day or two, and keep a trusty container of Rollaids at hand.
"We were starving out of our minds when we decided to call a pizza place. Domino's delevered 45 minutes later, and we were all satisfied. The next day, in the afternoon, I wasn't feeling good, when I realized: The Domino's Effect has started...."
by Brandon Brown June 20, 2005
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A phenomenon in which an individual consumes a large portion of fast food, and subsequently has to shit only 10 minutes later. The Domino's Effect defy's all that is known about the digestive system. This commonly occurs after eating food from a Domino's pizzeria, but may also occur with other places such as Taco Bell.
Man 1: Oh my god. I literally finished eating my cheesy bread 5 minutes ago, but already need to take a dump.

Man 2: Yet another tragic, yet mystifying case of The Domino's Effect.
by thebetterfriend2 November 20, 2009
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The awkward stomach and bowel movements the day after eating a Domino's pizza.
"Tim are you okay?"
"No, I've had the trots this morning after last night's pizza"
"Oh, that's the Domino's Effect"
by K-Dogg 81 July 18, 2018
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A person at a party who moves around continuesly asking people out, all attempts at gaining companionship fail and result in the person gaining a reputation as being a weak 'player' or just being scummy person without much moral fibre.
Tom's attempts at seduction were in vain as he has already suffered the consequences of the dominoing effect
by H3wbacca September 14, 2021
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The new definition of the Domino Effect is where you have no hope of getting a quality job and your last resort is to work for Dominos Pizza.
Jimmy: Hey man, im 25 and i cant seem to get a job at all these days

Mark: Oh man,, i can see you heading down the path of The Domino Effect
by Sparky-G November 26, 2006
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