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a feeling of being sadness but you also have a good sense of humor.
"how are you doing?"
"oh you know being a depresso espresso"
by Amandayyeeeee December 31, 2017
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A phrase brought to popularity by Malainey (not Tom). It is used to describe someone who is feeling depresso. It has the complete opposite affect of a regular espresso.
Jimmy has been a bit Depresso Espresso recently
by CarrotCuntCasey October 24, 2018
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