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ass-crack cocaine 

a figurative drug (in the same way as imbecilium) that makes the user act like an asshole or even a douchebag.
Whatever you're on to cause you to make these "jokes" and act like a douchebag when you're usually fun to be around must be some pretty powerful variant of imbecilium or ass-crack cocaine

gay mooch asshole greedy cocaine 

Nick: Why is Darian such an asshole, he won't fucking leave me alone.
Harvard: what is wrong with Darian?
Nick: Darin is such a gay mooch asshole greedy cocaine bastard fuck!