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From the acronym 'BFFL', which stands for 'best friends for life'.
He was acting like we were biffles, even though I hadn't heard from him in years.
biffles by Hudson December 23, 2004

biffleship

A bond between two people that have a mutually amicable love and respect for each other, recognizing that this bond will not be broken within the bounds of physical life.
"Come over to my house, where we can feel the full force of our biffleship!"
biffleship by harryandron4eva April 19, 2010
'Biffles' is short for "best friends for life".

Contrary to popular opinion, biffles can in fact become more than friends and still be biffles.
Even though my biffle and I got married, we're still biffles :)
biffles by 1L Bhallu February 18, 2010
A best friend for life. Comes from the acronym, BFFL.
Liz and Erica are totally biffels.
Biffel by Erica P. December 28, 2005

Biffles for Liffles 

Best friends for life... for life.
"We're not just friends, we're not just best friends, we're not just biffles, we're BIFFLES FOR LIFFLES."
Best Friends.
like BFFL.
thank you Olga for that great word.
i am forever worthy or you and it!

Olga and i are biffel's. i got it's back. it's got mine!
Biffel by ilovejonasbrothers October 19, 2008