best stuff 

Means high quality drugs:

Pure Columbian heroin
Crack-Cocaine ("rocks")

Quote from hit tv show "Chappelle's Show":

Tyrone Buggums at the class talking with little kids:

"You can't fly on drugs, only on the "best stuff". But you can't get the "best stuff", I don't!"

best stuff by BabyBoss October 28, 2009

teh best stuffs

Misspelling of "The best stuffs"; meant to be a generic term for anything worth viewing.

I just saw this PLA website. It has teh best stuffs!

teh best stuffs by Vash Westland October 18, 2003

teh best stuffs! 

Needs no explination, but if dumb, it means "better than anything else. period. explination point."

d00d! c4c7u5 is 73h b357 57uff5 (dood, cactus is teh best stuff- for teh phr34k3r22"

teh best stuffs! by Tim Wochomurka March 19, 2004