The process by which a song's title is inferred through the lyrics, even though the actual title of the song is different.

Named after the song "Bring Me To Life" by Evanescence, which many nimrods erroneously believe to be called "Wake Me Up Inside." However, this phenomenon is not limited to this song only.
Person A: My favorite song is "Wake Me Up Inside" by Evanescence!
Person B: I believe the song is called "Bring Me To Life"
Person A: Shut the fuck up!
Person B: Just another case of "Wake Me Up Inside" syndrome...
by TheBeigeDolphin October 15, 2016
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When your wealth becomes so massive, that it affects your decisions.
John: Bro.. you have so much money fr.
Samuel: Yea bro. Money is up but the syndrome is down
by mynodisused August 14, 2022
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Up Syndrome is when someone with Down Syndrome is high off weed
Bro is he ok”
Nah he’s having a bit of Up Syndrome”
by Wild Warren December 13, 2020
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when you have so much down syndorme it inverts itself
"jozlen sussy jol" up syndrome
by jolzen December 2, 2022
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When someone tends to hover above chimneys
Dolly has up syndrome, look at her hovering
by Dick Massive July 1, 2021
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A person who is seriously ugly to the point no one wants to look at them without protective goggles.
That guy has up-syndrome, he’s such an uppy
by Lickle bump February 26, 2022
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When someone looks like they have down syndrome but they actually don't

Or do they
he looks up

he look he has up syndrome
by v842 November 18, 2022
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