A transphobic slur. Like the n-word for transgender people (People whose sex misaligns with their gender.)
Keith: Your ‘girlfriend’ is a dude, total trannie
Victor: Dude, that’s transphobic! My girl is a girl, dawg. And anyway, you’re cis; you can’t say that word.
Victor: Dude, that’s transphobic! My girl is a girl, dawg. And anyway, you’re cis; you can’t say that word.
by Smol Trans Girl November 29, 2020

Some Ugly Guy: Dude, that chick has a penis...she's a Trannie.
Another Ugly Guy, with an afro: How the hell would you know!?
::They both get into a fight::
Another Ugly Guy, with an afro: How the hell would you know!?
::They both get into a fight::
by Hank Tanks on Crank June 28, 2004

by TranniesSeething September 9, 2021

In mechanics, a vehicle's transmission.
by Downstrike June 4, 2004

"Fuck. I have left the trannies of the trannies in the back of the tranny."
- A fetish photographer.
- A fetish photographer.
by Viz March 16, 2003

by anon-e-mouse April 11, 2005

by Urby Ambcock December 9, 2008
