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A tissue rush is when one is nearing climax during masterbation, they are so lost in the moment that they forget to reach for a tissue and have to do so at the very last moment, sometimes reducing the quailty of the wank.
Mark: "God last night I was watching this amazing porn. I got so into it

Joe: "Was there a tissue rush?"

Mark: "Yes, yes there was."
by TheMarsh January 30, 2009
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