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The Big O 

Defined as the female's climax in response to sexual stimulation.
My sweet babboo gives me The Big O and I am his slave for a week.
The Big O by THE REAL JULIA June 22, 2006

The Big "O" 

"The Big O" with a woman has been elusive for Pete for many years.

The Big O 

There has never been a basketball player more versatile than The Big O.
The Big O by IcebergSlim78 March 13, 2009

the big o 

an animated show about a giant megadeus (mech), the Big O, and it's Dominus (pilot), Roger Smith.
The Big O airs at 1:30 am on Adult Swim
the big o by Paradigm City May 13, 2005

the big o 

the big o by Nick-names January 23, 2009

the big o 

The semi-official, fresh-from-marketing nickname for Omaha, Nebraska. Latest in a number of slogans designed to give Omaha an "image", this one seems to have stuck, the fact that it has not enhanced Omaha's image one jot notwithstanding. Most commonly used in "buy the big O"; i.e., keep your dollars in the local economy.
Remember to support your local retailers and buy the big O!
the big o by regular_gonzalez November 5, 2005