To lay the smackdown on someone, to annihilate them or to win an argument or fight with ease.
Man 1: 'Dude, this girl Nicola, she came at me all like, "dick, why you been acting so fucked towards me?"'
Man 2: 'Damn, what did you do?'
Man 1: 'I laid The Smackdown on that fuckin' bitch!'
Man 2: 'Word.'
by B to the Rittain August 19, 2006
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1) A contraction of two words ("smack" and "down") popularized by WWE wrestler-turned-actor The Rock that refers to the inflicting of a beatdown of epic proportions upon "jabroni"s' "candyasses". Sometimes used in a bastardized form of Elizabethan English.

2) The name of the Thursday night WWE show on UPN created by Vince McMahon originally as a show of respect for his champion, The Rock, who commonly used the term. Now it is merely a place where stars' careers go to die.
1a) The Rock prepares to lay the smackdown on Triple H.
1b) Know your role and shut your mouth before I layeth the smacketh-down on ALL your candyasses!

2) Chris Benoit has left SmackDown! for RAW to finally earn some redemption for his career.
by SteelPhoenix March 09, 2004
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Refers to any confrontation or fight (wheater it is physical or not).
The debate between the two politicians was a smackdown.
by Nick_S_G February 25, 2010
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Smackdown is The Rock show or was until The Rock left to become an Actor.
Smackdown is the new WCW Tunder show.
by Fightinggato April 02, 2004
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A WWE wrestling program that airs on UPN every Thursday nights. Features stars such as John Cena, Eddie Guererro, Rey Mysterio, JBL & The Undertaker. Many wrestling fans see this show as inferior to WWE's other show, Raw which airs on Spike TV every Monday night.
"It's time for Smackdown! Give me the fuckin' remote!"
by Just The Facts March 20, 2005
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The WWE show, shown on Thursday nights, which carries the substandard WWE wrestlers. Is the competition for WWE RAW, which is the authority of WWE TV shows. Their titles are the WWE Championship, WWE Tag Team Championships, and the Cruiserweight Championship.
Damn, no wonder he's not on RAW; SmackDown's the only suitable place for his suckiness.
by Dodd December 06, 2003
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You say it when you've bested someone at anything. Like if you win a card game, beat someone at a video game, or a race, etc.
*You beat someone in Fight Night Round 3*

Yeeaaah boy! SmackDown! F*ck 'outta here, you can't beat me!
by Sendo August 01, 2007
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