When one is high from marijuana and drunk from alcohol at the same time.
I've been screwballing all night.
by SouthJersey March 21, 2009
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Screwballs means 'crazy people'.
'I just met two real screwballs'. Oddballs. Fruitcakes. Loaf heads.
by Dannyloco1 December 25, 2011
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The worst movie of all time. If googled, there are only a handful of mentions and it is next to impossible to find a VHS copy of it anywhere
I saw Screwball Academy and the last line was, "...have fun, cause things don't go 'round forever."
by Nathan Tiberius October 9, 2007
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pouring a vanilla milkshake over your penis, freezing it using a walk-in freezer to make a solid frozen layer of milkshake on your penis, and proceeding to have sex with a girl, while rotating your entire body around the axis of her vagina.
"Last night, I heard that Steve gave his girlfriend a Nebraska Screwball!"
by definitionman345433 July 14, 2009
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To understand the perpetrators of this crime see labrat.

Degenerate Lab technicians consume test tubes of semen orally and when they arrive at the last tube a system call screwball scramball comes into play. The test tube is thrown into the air and the labrats fight for the male reproductive fluid.
"okay guys were down to the last tube of the good stuff, SCREWBALL SCRAMBALL MOTHER FUCKERS".

Sam " yo chill it was totally awesome ya, there was like ten of us in the lab last night and i won man"
Mick " what, the srewball scramball, that's totally rad bwana"
by jebusmoore December 27, 2007
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One who lives and dies by the lemon and lime. They often lose themselves in the shiny emerald surface of the can, gazing at its radiance for extended periods of time. Sprite screwballs are stereotypically in awe of a glistening cold Sprite's ability to quench thirst. There will often be numerous empty Sprite vessels littering their work spaces and private rooms. A Sprite screwball's recycling can often fills up long before their garbage can does, but not without a heartfelt goodbye to each spent can. There is also likely to be individual Sprite surprises scattered throughout a screwball's home, intended to be saved for a "rainy day". Praise be LeBron and the Sprite cranberry.
"My husband is a Sprite screwball; his desk is covered in empty cans and he won't even acknowledge dinner unless I made sure to buy him his daily twelve-packs of Sprite."
by VoltronPrime April 25, 2022
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the two ball screwball is when you are reverse titty fucking a girl while she is sucking/licking your testicles.
dude i two ball screwballed the shit out of that girl last night
by coreyvdw July 21, 2006
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