A beautiful girl who's pretty and outgoing and gives the best head even though sometimes she's a bitch she's sexy as a mother fucker
"Santana A bad one "
by Nick Green May 6, 2017
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A nice, beautiful, hot, caring, funny, and wifey material girl. A honest friend ,never lies , and sometimes annoying. Has long curly hair, nice lips, and big thighs. Also is single.
Boy 1) Who is that hot girl with the curly hair over there .

Boy 2) oh you don't know her ? Thats Santana.
Boy 1) is she single???
Boy 2) yes she is.... you should go ask her out
Boy 1) I will
by Felica145 November 17, 2016
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The best friend a girl could have, funny with a great smile. White girl that loves black dick, A LOT. A lady in the streets but a freak in the streets... or backseat of a car.
"who is that girl with that black guy?"
"not sure, she's hot though so she must be a Santana."
by 666birdhomes March 24, 2015
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A charming boy with curly hair that give good sex and will please any girl he will be rich and play in the nba with the love of his life all girls fall in love with his big cock
Santana has a big cock
by Tanaman April 12, 2019
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A TOTALLY AWESOME LATIN ROCK BAND, LED BY THE GUITARIST OF THE SAME NAME.
There's only one Santana, his first name is Carlos - and he plays the meanest guitar in the world !!
by .l April 28, 2014
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THE KING OF COCAINE, IN PORTUGAL THE TITLE IS GIVEN TO THE BIGGEST COCAINE DEALER IN THE GANG
U have to go to Santana if you want some
by Cardo970 August 26, 2017
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THE QUEEN OF LIMA HEIGHTS.

and also the character who insults everyone and keeps you entertained when you have absolutely no hope in the show.
person 1: who’s that girl who sang trouty mouth? she popped off

person 2: santana lopez of courseeee!!!!
by wowowowowoowwoowowowow March 15, 2021
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