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1. short for "organic chemistry."

2. an extremely difficult course that one takes, usually during the second year of college for prospective Pre-Med students. It is associated as a "weeder" class for hopeful students, as many people drop the class before they complete it.
"Holy fuck man, I don't get any of this orgo stuff at all."

"Yeah, ikr?"

"I want to drop this class, but I don't wanna look like a fucking retard. What should I do?"

"Idk man. Idk."
orgo by Omniscient Dumb Fuck November 16, 2011
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Sometimes referred to as ochem by holier than thou west coast students when referring to organic chemistry.
I can't go surfing dude! I have to study for my orgo exam tomorrow.
orgo by The Boomhower April 29, 2011
Related Words
orgo

A term for "organic chemistry" that stuck up rich ass east coast students use because apparently the east coast is too good for conventional usage of abbreviations. Many east coast students like to call it a "weeder" class for premed students, but on the west coast, pre-med students know better than to be discouraged by a single class, so such a trend does not exist.

East coast student: "Hey what do you think of orgo?"
West coast student: "Sorry, we only speak English over here. I don't know about any orgo, but ochem is a pretty good class to take."
East coast student: "Hey what do you think of orgo?"
West coast student: "Sorry, we only speak English over here. I don't know about any orgo, but ochem is a pretty good class to take."
orgo by relaxin' October 15, 2010
Abbreviation for "Organic" in the context of organic chemistry - regarded as among the simplest of many upper-level ivy-leauge chemistry sequences. Also commonly employed as a weed-out class for premedical students. However, the material is simple, and the tests are easy. Especially lab commandant's Parr-Hydrogenation tests.
Dude, that orgo final was mad easy.
orgo by NUndergrad January 16, 2006
A girl who is not inclined to partake in sexual activities and must therefore vacate the premises.
Ex. 1:

Bro 1: to Orgo Girl: You baby you DTF?
Orgo Girl: No way you perv.
Bro 1: Well then you must leave... OrGo.

Ex. 2:
Bro 1: Yo is she DTF?
Bro 2: Nah she's Orgo dude.
Orgo by Carltonbanks October 18, 2010
A WIERD person that hates basically everything
Eww, Josh is a orgo
Orgo by Hi.......? January 8, 2018
The most dangerous organisation in Europe. Ran by Max
person 1: Yo bro Orgo just raided me.
person 2: ratio 😹😹😹😹😹
Orgo by Orgofijkefsefrgrsgrdg June 17, 2022