Meaning that a thing (such as a wastepaperbasket) or a place (such as a garden shed) is absofuckinglutely stuffed to capacity and can simply hold no more without the lid shooting off or the door(s) bursting open.
(Angie): Craig, can you please put that cat carrier in the garden shed?
(Craig): Sorry, no can do. There'should no room at the inn.
(Craig): Sorry, no can do. There'should no room at the inn.
by Telephony June 2, 2014
The act of inserting all the individual pieces of a nativity set up your anus until there is "no room at the inn"
"I tried to sit down for Christmas dinner the other day, but the night before there was no room at the inn so I couldn't"
by Ricky Beans December 4, 2007
a women with 3 men penertating her at the same time.one in the mouth,one in the vagina and one in the bum hole
by fishermundo May 10, 2011