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noun: A niece or a nephew.
adjective: of or pertaining to a niece or nephew.

plural: niephews

http://www.askoxford.com/asktheexperts/faq/aboutwords/siblings?view=get
"I have four niephews: three nephews and a niece."

"Three of my niephews are my first sister's children (two sons and a daughter), and my fourth niephew is my second sister's child (a son)."
niephew by imperatrix March 27, 2009
When you don't know if you'll be having a niece or nephew.
I can't wait to figure out what my niephew is!
Niephew by Kjtheblogger June 3, 2017
My niephew Jade identifies as nonbinary now...
Niephew by T17745 May 1, 2022
Noun: (nee-few) The gender neutral form of niece and nephew
I have 7 niephews.

With my 8 nieces and 6 nephews I have a total of 14 niephews.
Niephew by Zip.Kelvin January 8, 2016
Gender neutral term to refer to the relationship of a sibling's child (niece or nepew). The word is a portmanteau of niece + nephew
My brother's five children (of various genders) are collectively my niephews
niephew by TitiFarnico August 14, 2023
A niece that may or not be transitioning to a nephew or Vice versus.
E.g. “My niephew insists on using elf ears when we go shopping!”
“My niephew just asked me if they are hot. Wtf do I say to that??”
Niephew by Coolguy228 December 18, 2024