(1) International Federation of Science
(2) Ickle Fickle Sassykins

(3) A natural phenomenon where the concentrated levels of black sass within an area exceed 75%.
Oh dang, look at that! It's an IFS!

Bro, I work for the IFS.

Hey, what's up IFS?
by Dichlorodiphen February 11, 2015
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I keep breaking my cv axles with this damn independant front suspension.
by muthafukin July 14, 2005
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Incredibly Fucking Stupid
This acronym is commonly used in internet forums and chat rooms.

"How do you know if water is wet?"

by Lookit January 23, 2009
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Similar to IBS,Irritable Friend Syndrome can occur when a friend unexpectantly morphs into an obnoxious bitch, but you have known them too long to severe the relationship.
Help me! I have serious IFS with my best friend since 7th grade and I don't know how to tell her to shut the hell up without hurting her feelings.
by Jeanniebean137 October 25, 2007
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My god, look at that fire crotch, and an IFS to boot!
by amotiser August 25, 2010
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Insufficient Funds Syndrome. Usually a diagnoses will be performed by your bank, instead of your doctor. Symptons include, but are not limited to; Having to put all your groceries back at the supermarket, Hearing the cashier say, "sorry sir, but you cannot purchase porn and cigarettes because your card has been declined.", And the most severe symptom is having no life, no friends and definitely no girlfriend. Not all people with IFS experience these symptoms, but do not be fooled, this syndrome is not one you would like to contract.
"Dude, I went to the bank earlier and they told me I have IFS, how do I tell my girlfriend?"

"I'm afraid I can't #crackacoldonewiththeboys tonight bro, I have IFS."
"I really want a fidget spinner, but with IFS, my choices are limited to watching videos on YouTube about 11 year old kids who are already fidget spinning pros, when I know that I would be the best in the world if I just didn't suffer from IFS."
by Kaper_215 June 26, 2017
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Internet Faggotry Syndrome, or IFS for short, is where a seemingly normal human being IRL becomes a total faggot online. They transform themselves entirely, much as Optimus Prime does.
Person with IFS:

IRL: Hey man let's go back to my place and watch the game, I hope the (local team name here) win!

On the web: lol! do u want to come over n watch the game? lmao its gona b such a kewl game! lol
by January 20, 2008
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