HSD

an acronym, commonly used on the Internet, meaning "holy shit, dude", derived from the infamous South Park feature film, 'South Park: Bigger, Longer, & Uncut' quote - Kyle Broflovski
Mr. Garrison: What did you say?!
Eric Cartman: Oh, I'm sorry, I'm sorry. What I said was: How would you like to SUCK MY BALLS, Mr. Garrison?
Kyle Broflovski: Holy shit, dude(HSD)...
by BenJAMSTER June 25, 2008
mugGet the HSD mug.

HSD

High Sex Drive.
Normally owned by males who masturbate to much. Can end in death of their girlfriend.
Unless the girl has it too...
Boy: Come here, *Grunts* Ooooh more.
Girl: Fuck stop that hurts!
Boy: You like it!
Girl: Stop! You have HSD...
by GeeHSDx October 24, 2008
mugGet the HSD mug.

HSD

Acronym for 'hardcore street drugs'. Usually means heroin, crack, meth, etc.
Yo, let me get some of those HSDs!
by slsanity August 25, 2013
mugGet the HSD mug.

hsds

Holy Snapping Duck Shit - an exclamation of total surprise.
Holy snapping duck shit! When I posted hsds I didn't mean Hardcore Satan Death Sex
by JMannus May 26, 2011
mugGet the hsds mug.

HSD

Gigi:“HSD~”
Nathan:“WTAF!”
by Fincae777 May 21, 2021
mugGet the HSD mug.