HSD 

an acronym, commonly used on the Internet, meaning "holy shit, dude", derived from the infamous South Park feature film, 'South Park: Bigger, Longer, & Uncut' quote - Kyle Broflovski

Mr. Garrison: What did you say?!
Eric Cartman: Oh, I'm sorry, I'm sorry. What I said was: How would you like to SUCK MY BALLS, Mr. Garrison?
Kyle Broflovski: Holy shit, dude(HSD)...

HSD by BenJAMSTER June 25, 2008

HSD 

High Sex Drive.
Normally owned by males who masturbate to much. Can end in death of their girlfriend.
Unless the girl has it too...

Boy: Come here, *Grunts* Ooooh more.
Girl: Fuck stop that hurts!
Boy: You like it!
Girl: Stop! You have HSD...

HSD by GeeHSDx October 24, 2008

HSD 

Acronym for 'hardcore street drugs'. Usually means heroin, crack, meth, etc.

Yo, let me get some of those HSDs!

HSD by slsanity August 25, 2013

HSD 

Means “Hey Sugar Daddy”

Gigi:“HSD~”
Nathan:“WTAF!”

HSD by Fincae777 May 21, 2021

Hoenn Special Disease (HSD)

A satirical gaming term used in Pokémon communities to describe a player who completely sabotages their own tactical advantage by over-prioritizing raw damage. Specifically, it refers to a bruiser (whether a mixed attacker or not) using moves that make them more frail, especially while in Strong Style. It can also refer to a glass cannon (mixed attacker or otherwise) using Strong Style and/or moves that decrease their action speed, leaving them completely vulnerable to multiple consecutive counter-attacks.

Player A: "The boss just took three turns in a row and wiped my team after I clicked my strongest move. This game is unfair!

"Player B: "You have a classic case of Hoenn Special Disease (HSD). You used a Strong Style recoil move with a glass cannon, completely wrecked your own action speed, and gave the enemy a free win.

Hoenn Special Disease (HSD) by East Sea Gastrodon's Ice Beam June 14, 2026

HSDQ 

An abbreviation for 'Half Story Drama Queen', used by those soliciting undeserved attention by posting deliberately vague Facebook Statuses.

This really is like hell on earth... What have I done to deserve this! :'( HSDQ

Would love for one day to go by without something going wrong...

needs a miracle right now :(

Bereft with a capital B and nobody cares...

HSDQ by clarkshooz October 10, 2012

HSDR 

Headline Sucked, Didn't Read.

In a virtual world of fake news and click bait, it's a good way to summarize your sentiment about the article without reading it.

"He’s black, a practicing Muslim, and supported Bernie Sanders."

Mmmmmmmm identity politics! I'm sure Keith Ellison loves being known for his color, religion, and who he supported. He sounds so accomplished and qualified! HSDR. (Headline sucked, didn't read).

HSDR by pbrewsky November 27, 2016