go and... INFORMAL used to express disapproval of something that is done:
He's gone and lost (= He has lost)that wallet I gave him for his birthday.
Mike's really gone and done it now - he'll be in terrible trouble for breaking that window
this phrase simply put means that the object of the abuse is quite mad in the head. therefor should instead of fucking off "GO AND THROW SHITE AT THE MOON"
insane man - moo boo hoo too coo
sane man - christ on a bike that mad in the head person is dribbling shit again i so wish he would fuck off and go and throw shite at the moon