The Gambino crime family is one of the "Five Families" that controls organized crime activities based in New York City, United States, within the nationwide criminal phenomenon known as the Mafia. Based in New York City, the group's operations extend to much of the eastern seaboard and all across the nation to California. Its illicit activities include labor racketeering, gambling, forced prostitution, loansharking, extortion, murder for hire, solid and toxic waste dumping violations, construction, building and cement violations, fraud and wire fraud, hijacking, pier thefts and fencing.

by Elly Gambino July 10, 2008
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Slang for a hot young Italian thug.
"That guy Vinnie is a total Gambino."
by That Sublinal Kid December 26, 2016
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A singer, rapper, actor, writer and many other things the man is just a god. Donald Glover lookalike
Gambino is unreal
by alexlfc23 January 30, 2017
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A NPC character on Gaia Online. He heads the infamous G Corp, and is currently in a heated battle with the Von Helson sisters (Two other NPCs), because they kidnapped his son, Gino Gambino. Gambino is a crazed man who has lost his sanity in the search for his son, and in that craze, he asked for donations from the Gaian users and built a giant tower. The tower itself was a monument to Gambino's power and lust for revenge, and so, when he was shot down by a mysterious cloaked figure, the tower fell down with him.
Oh no! Gambino is dead? Now who will host the events?!
by Amanda W June 8, 2005
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Slang varation of 'making gay-love'.
Initially startet out as a joke in a few towns in new mexico around 1985-86. But the term quickly became common slang in the upskirts of major american cities with latino influence.
The Gay man Jose made "Gambino" on another Gay man - called Rodrigez
by Niels January 12, 2004
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Gambino: (n) "gam-bee-no"
A childish person, referring to one who makes stupid mistakes or is a tool.

Also known as: "Bino"

Synonyms: lil boi, lightskin, tool, fag
Ramone: "Devante still believes in Santa"

Darnel: "What a gambino!"
by slimmest shady January 4, 2015
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