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Basically telling someone or something to fuck off. Term coined by my girlfriend's mom.
That can go fuck.
He can go fuck.
Seriously, she can go fuck.
Go Fuck by Frenchfry2016 August 22, 2016

Go Fuck Your Selfie 

A retort one gives when someone takes too many selfies.
*Max takes a selfie in class*
Victoria:Hey Max, why don't you go fuck your selfie!
Go Fuck Your Selfie by mrperson123 January 31, 2018

go fuck somewhere else 

go fuck somewhere else another way to tell someone to fuck off and go fuck themselves at the same time when you are not afraid to use stronger profanity
dude wheres my goddamn candy

man i dont have your goddamn candy go fuck somewhere else

no dude give me my goddamn candy and go fuck somewhere else

man you better stop badgering me about your goddamn candy and go fuck somewhere else

dude you are really uptight

man what do you expect to get from me im telling you to go fuck somewhere else

ok dude i get you

Go fuck yourself 

A colorful method of telling someone to either; a) shut the fuck up
b) go the fuck away
c) go annoy the fuck out of someone else
d) an all inclusive phrase of general distaste which includes a-c as well

Go fuck Yaself 

Guy 1: Hey Nickyhow about settin me up with that cute little sister of yours?

Nicky: Hey, how bout you go fuck yaself.
Go fuck Yaself by Mr. Swagger January 26, 2011

go fuck yourself 

When someone tells you to go fuck yourself, they are encouraging you to shove your penis up your own asshole by bending it backwards. Or, if you're a female, to grab the nearest phallic object(s) and penetrate your orifices repeatedly. The connotation is that you'll probably enjoy it and will stop annoying everyone.
Broke Ass: "Hey man, can I have one of your beers out of the fridge?"

Working Man: "Go fuck yourself."