Frisco Special Share definition Flag Slang term used in the drug world meaning a narcotic concoction of LSD and Heroine. Hey Mike, while your there, buy me a frisco special, will ya'? Frisco Special by Héctor Andrés Mayoral May 3, 2008 0 0 Get merch Get the Frisco Special mug. Buy Now — $32.95 See more merch