The worst sibling in the family. The "Fredo" could otherwise be successful but in comparison to their otherwise more successful or better looking siblings they are failures.
Chris Cuomo is the Fredo of the Cuomo family.

Other Fredos include: Ted Kennedy, Beau Bridges, Daniel Baldwin, Ozzie Canseco, Jeb Bush, Jerry Van Dyke, Liam Hemsworth, Gerald Wilkins, Randy Quaid, Vince DiMaggio, Frank Stallone, and Clint Howard.
by Actionlad August 14, 2019
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The birth name of CNN Anchor Chris Cuomo.
Fredo Cuomo is an Anchor at CNN
by LBC_Andrew August 13, 2019
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To bang 2 cocktail waitresses at the same time - adapted from "The Godfather" and brought back by Trent (Vince Vaughn) in Swingers.
Daddy's gonna meet 2 girls and pull a Fredo.
by J-Dubs January 27, 2005
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CNN anchor Chris Cuomo, the dumb, weak, loser brother
Fredo is the worst, lying and telling us it’s illegal to read WikiLeaks.
by Lord Stirling August 13, 2019
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The non ethnic slur used to describe the dopy brother type
Hey look at Fredo on tv. He is always misinformed
by Elephant77 August 14, 2019
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Another name for Chris Cuomo, a CNN anchor
by tyros2 August 13, 2019
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A fake slur promoted by a fake new anchor to express fake outrage while making fake threats of violence.
My name's not Fredo. My name is Chris Cuomo, I'm an anchor on CNN. You know, an anchor, like at the bottom of a lake along with my ratings. Fredo is from 'The Godfather,' he was that weak brother. Kinda like me. And they're using it as an Italian aspersion to trigger my fake outrage. So I can get people to tune in and see what a badass I am. Fredo is like the 'n-word' for us. No, really, it is. Punk-ass bitches from the Right call me Fredo. And now that I think of it, so does my girlfriend. I will ruin your Fredo shit. I will throw your Fredo shit down the stairs.
by #Q August 16, 2019
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