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a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother."
by yo mama's snatch March 15, 2003
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1) A phrase of agreement. Used when responding to a statement.

2) Another way of saying, "Of course." Used when responding to a yes/no question.

Both are heard in mostly urban areas, especially ghettos. Either that, or heard in an SUV driven by some white, suburban kid listening to rap.
1) Rodney: That was a great party last night!
Samuel: Fo shizzle ma nizzle!

2) Herman: Was that party last night great, or what?
Helga: Fo shizzle ma nizzle.

By the way, it appears many of the people who defined this word don't like black people. You might say that Rodney Basil doesn't like suburban, white people, but that's not so. I am a suburban, white person.
by Rodney Basil April 24, 2004
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for sure my --insert colloquial expletive beginning with "n"-- .

Just to clarify... The "izzles" and "izzos" were introduced to urban pop culture by Double Dutch Bus in 1981, however, Snoop took it to a new level. Snoop interpolated Double Dutch Bus (which was written by Bill Bloom and Frankie Smith) and originally performed by Frankie Smith (NOT the Gap Band).
Dizzouble Dizzutch... Double Dutch.
by ebloom November 8, 2004
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"fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"
by pixelfrenzy April 15, 2009
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Bodan: "you gonna come kick some white ass tonight?"
Rajib: "fo shizzle ma nizzle, im there!"
by harv1989 October 24, 2006
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This is not a word, period. It is some silly bullshit perpetuated my Snoop Dogg or P. Poodle or whatever he is calling himself this week. However, if you really want to judge it to the same standards as real words, it loosely means "Okay".
"Excuse me sir, do you have any Grey Pupon?"

"Fo shizzle ma nizzle!"
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