In the Midwest region, particularly Kansas, the word is used to refer to Methamphetamines rather than heroin, as heroin is rarely seen.

1. Heroin. Dope doesn't refer to any other drug. A dopehead / dopefiend is a heroin addict.

2. A common slang for good, beautiful, handsome etc.

A fuckin awesome metal and industrial rock band they DO NOT remix 80's songs so shut the fuck up.

really really good. Satisfying, great! You really like something

short for dopamine, which is actually a chemical realeased in yoru brain, when something "good" happens. Dopamine is realeased when you eat, and deppending on the content of what you consume certain amounts of dopamine realease.

Also this is realeased in sex, when you see or get something you like, like a gold watch, or when you have a good "trip" hence "DOPE" is used to describe certain drugs.

In the past, and still in some localities, any kind of drug, including “soft” drugs like marijuana. Currently most often used used specifically for heroin. Regional variation can cause confusion.

An adjective describing something awesome and chill. Most commonly referring to music.