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Don’t call me Shirley!

This line is spoken by Dr. Rumack, played by Leslie Nielson, in the film Airplane!
In one of the film's most famous scenes, former pilot Ted Striker (Robert Hays) discovers that both the pilot and co-pilot of Trans American Flight 209 have succumbed to food poisoning. Dr. Rumack asks Striker if he can fly the plane and land it. Striker responds, "Surely you can't be serious," prompting Rumack to say, with a straight face, "I am serious. And don't call me Shirley."
Julia seen Sharlene at the party and thought she was Shirley, so she said “Hi, Shirley! Nice hairdo!”. However, Sharlene didn’t take it that well and slapped Julia in the face “Don’t call me Shirley!” she huffed and left.
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...And don't call me shirley 

Famous line from the comedy movie "Airplane!". Used when someone uses the word "Surely" in their sentence. "Surely" sounds like "Shirley" when spoken, and therefore making sound as though your name is Shirley, or talking to someone called Shirley.
"Surely you can't be serious?"
"I am serious...And don't call me Shirley."