In the Sherlock Holmes books it refers to one of Sir Arthur Conan Doyle's stories, in which he refers to another case Sherlock worked on to do with some Vatican Cameos.
In the case of BBC Sherlock it is code for duck, as in get out of the way. It probably refers to another case Sherlock and Watson worked on not shown in an episode, in which only Watson knows to duck out of the way of, in this case, an oncoming bullet. Most usually used by Cumberbitches.
*Playing some sort of ball game*
Cumberbitch: "Vatican Cameos!"
*Everyone ducks*
by the-tall-one March 30, 2012
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Vatican Cameos is what Sherlock Holmes, from BBC Sherlock, shouts to John Watson when he’s finished opening Irene Adler’s vault and realizes it’s a booby trap (s02ep01). When in danger Holmes says a cue so Watson knows how to react properly. It’s their “safe word”.
Sherlock shouted "Vatican Cameos" and Watson threw himself on the floor without even thinking about it.
by Lalanda February 18, 2012
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this would be my girl freind.
jon guy goes out with cameo kuschel.
by jon guy April 21, 2003
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The annoying friend who calls or stops by (unannounced) and is off the phone or out the door in less than two minutes. Has a tendency to do this often and for no purpose.
-'What was that? I thought I heard the phone ring??'

-'You did, it was Greggo pulling the 'real-life cameo' again.'
by Stuvis September 29, 2009
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A game where most people come to when they are either banned or upset with Rogue Lineage. Usually femboys or fake e-girls will come to these areas, looking for clout, and sex. Usually gay people reside here, as it is often rare to see straight people. It is a very VERY toxic community, where people use the N-R slur with too many times to count. It is a rare occurrence, but there are some normal people here that seem pretty chill.
I can't wait to kill moderators in Cameo-Game-2 because they're ez.
by Cameo-Game-2 June 9, 2021
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Noun. When a recognizable or distinguished actor appears in a film whose cast are predominantly unknowns. Refers to the 2009 Best Picture Winner "The Hurt Locker," in which actors Ralph Fiennes, Evangeline Lilly, and Guy Pearce made brief cameos.
Lance Henriksen pulled a Hurt Locker Cameo when he made Screamers 2.
by LongMayBlues June 19, 2010
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