A crude term for an individual with an alarmingly large number of STD/STIs or love bugs, regardless of whether they show signs of them or not.
Shit Monkey: "That whore of a man, Testicle Tim, has slept around so much that he's finally contracted every STD known to man."
Fuckhead Fred: "Hey, he be gots them 50 Shades of AIDS!"
Shit Monkey: "You fucking dumbass, there are way more VDs than AIDS."
Fuckhead Fred: "Hey, he be gots them 50 Shades of AIDS!"
Shit Monkey: "You fucking dumbass, there are way more VDs than AIDS."
by Testostices McSourpenis August 30, 2019

Adjective;
The process of describing someone's prediction of an event, after said prediction turns out to be completely the opposite of what they said would happen.
The process of describing someone's prediction of an event, after said prediction turns out to be completely the opposite of what they said would happen.
Lew I thought you said Southampton would beat Leicester but they lost 9-0, "yeah I completely 50'd it"
by MrMaberly November 8, 2019

The rule of the internet (like Rule 34, Rule 63, etc.) which dictates that every fictional work will have a crossover with every other one at some point.
Person 1: Would it be funny if Sparklecare x JToH x Mega Man was a thing?
Person 2: Rule 50, man, rule 50.
Person 2: Rule 50, man, rule 50.
by an extremely depressed bandu September 17, 2023

The 50 shake is notoriously known to cause astronomically sized earthquakes powerful enough to cause houses too fall apart or even explode. BBC NEWS stated on August 25th, 2023 a local ohio resident reported neighbors blasting a song called the “thug shake” while reportedly doing the viral tiktok dance called the “50 shake” a few seconds later houses are seen toppling to the floor and causing earthquakes throughout the neighborhood.
by glorytactt August 25, 2023

by Cherrytopper July 12, 2024

by emokasper July 20, 2022

In Defense of Cultural Appropriation Slander Talking Smack Put-Downs Comedy, Light-Hearted Social disparaging remark, Sang Slang Reversal Psychology. Fifty Cent is known for being a Criminal thug and Sly Business consultant on the Low with unconventional ways of committing retaliation against his enemies. Using Reputation and CELEB STATUS including Popularity Money Guns Drugs and Mobb like tactics to Influence an unfair bias against others.
by Mat Bat September 4, 2019
