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motherfucker 

This is often used as a pronoun for people in the same "game" or institution as the speaker, going through the same shit as the speaker, and at the same time, are demeaned using this word because they tend to -just like the speaker- look out for their own interests.
"These motherfuckers need to realize that if they do dat shit again, there's gon' be consequences.
motherfucker by jfz October 26, 2008
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Motherfucker's 

A word often used when someone is excited
Steve : Graduation tomorrow night Motherfucker's!
Kiersten : Gee Steve I didn't know you cared!
Steve : I don't I just told Chad that so I can have the night off!
Kaylee : Why the hell would you do that?
Steve : So I can make love to my Judy!
Kiersten : You lied to your boss so you can fuck a blowup doll!
Chad : Hey Steve it's not nice to lie so you will be working tomorrow night or your FIRED!
Steve : Ok sorry Chad i'll work!
Kiersten : Look's like Steve's working tomorrow night Motherfucker's!
Motherfucker's by SlopNChop July 20, 2018

yeat motherfucker 

Common phrase/expletive used in 201S of Third North used in both board and card games.
Lets play a rousing game of "Yeat Motherfucker!!"
yeat motherfucker by Sarah & Kai September 21, 2004

Fat Rat Motherfucker 

Fat is just rude. Rats are disgusting. So Fat Rat goes fine together, but doesn't sound right. Therefore Fat Rat motherfucker just another level of Fat Fuck...just worse
Say your boss pisses you off to the point in which the word fat or fat fuck, just doesn't settle with you. Fat Rat Motherfucker is pretty insulting, personally i don't think anyone would like to be called a rat or fat rat either, so Fat Rat Motherfucker just makes it more fun to say.

Motherfucker 

A term commonly used in jail by inmates to describe other inmates who cannot be raped, assaulted, or otherwise hurt due to the fact that they can, in one way or another, avoid or escape their advances.
That white boy is a Motherfucker, we were going to take 'em to the pit but he snitched to the guard.
Motherfucker by SQBastard May 16, 2011

Motherfucker 

An individual who partakes in sexual intercourse with female human creators.
John just knocked up another mother, what a motherfucker!
Motherfucker by the J Man February 27, 2015

Mega Motherfucker 

A person with a massive 12" cock who fucks mothers.

Also an asshole of epic proportions
"Wow Sam is really a Mega motherfucker"
Also
"Oh My God Sam is a mega motherfucker, i hate him so much