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Downing Street

Anything That Brings On Depressive Episodes Or Persistent , Otherwise Known As A Downer
The Situation Is Killin My Good Vibe ! Am On Downing Street Man
by The V ONE 2nd To None September 12, 2019
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Downie

Down syndrome, also known as trisomy 21, is a disease with a connection between mental disability and physical malformation. A downie is a person with this condition.
Marco is a boy who was born with down syndrome. He is going to a special school with other downies.
by TheAlmightyDario April 6, 2020
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Downie

someone who says super dumb shit and probably has down syndrome
"look at jackson Dutschke, hes got a small pp and is a huge downie."
by JacksonIsGayHeToldMe September 6, 2020
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downing an allergy

to down and allergy is to drunkenly drink your friends semen unknowingly
“man i got so drunk at the party i downed an allergy” downing an allergy aka drinking someone’s nut
by confused antonym November 10, 2020
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Downing the Guinness

Supping lots of Guinness on the couch while watching the Wescht Ham.
Did you see Neily Downing the Guinness. It's something to behold.
by TheCornhole69 December 11, 2020
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Downing

Sticking your hand so far down someone’s pants, you are considered “downing” them
Dude, you were “downing” that chick like nobody’s business!
by anonymous December 19, 2020
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Downing Street

Where Bojo and his gang hold " work meetings" aka parties.
"Bring your own boozes, party at no.10 downing Street."
by Kitkat21 January 17, 2022
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