Puff 

Slang for calling someone a pussy

Kristen is being a puff and won’t take the shot of captain morgan.

Puff by Mac and lain October 21, 2019

puff 

pregnant ugly fat friend, a subclass of the DUFF

My exgirlfriend got knocked up. Now she is a PUFF.

puff by rock082082 July 25, 2006

puff 

life, all your breaths

never in all my puff

puff by *burp* July 24, 2008

puff 

Puff/adjective ~ Awesome, wicked, cool, the ultimate.

That game last night was so puff!

puff by Gonzooo April 10, 2006

puff 

to fart

EW, why did you puff? now it smells bad

puff by car1y03 August 31, 2010

puff 

the leader of the dirty dozen in the 1970's in phx az. one crazy sick mother fucker

"things have really chilled out with the dozen, not so many prime time news clips now, not like when puff was president"

puff by nobody in phx June 19, 2009

puff 

fart

i puffed :D

puff by sydney delonge January 24, 2011