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A ghetto, rude,obnoxious,annoying,loud and uncivilized woman or girl, also referred to as a hood rat. Continuously gossips about others and can't seem to get her life together.
Yo man, that girl Keisha is a skeezer.

what a skeezer

attention Houston, the skeezer is approaching (joke)

your baby moms is a skeezer.
Skeezer by ncalvin01 April 4, 2010
"Hook me up with some of that steezy."
steezy by erik January 17, 2004
1.
a) A woman who leaves a good relationship with a man who is loyal and good for her when whatever problems frustrating the relationship are fixable.

b) A woman that leaves a man who is loyal and good for her using the excuses "i don't want this anymore" or "i want something different" and supplies insufficient reason and warrant for such, and also uses a supposed list of things that she doesn't like about the relationship without giving the boyfriend prior ample communication about the alleged problems in the first place, and also unjustly refuses the boyfriend a chance to fix the problems.

c) A woman who leaves a man who is loyal and good for her for a jerk that will most likely end up playing her the way said loyal boyfriend would never do.

2.
A generally disloyal and unfaithful woman that is easily swayed into conversation with a random guy, and eventually into bed. They often dress liberally and are found at parties, clubs, or any general place of sociability.

3.
A woman that does not care about hurting others, just as long as she gets what she wants.
Examples:

"So whats been going on with you and your girl man?"

"Man we broke up the other day out of nowhere, for no reason."

"After all the stuff you've done for her??"

"yea man, when i ask her why, she just gives me a load of bullshit."

"Man don't worry about that shit, she's a skeezer, you deserve better"

-----

"I went to the club last night and i bought this girl a drink for no reason"

"What do you mean no reason?"

"She looked like she was gonna talk to me, but she just drank it and left... what a skeez."
Skeez by therighteouscrusader August 20, 2011
have sex; fuck (according to Body Count's lyrics - Evil Dick)
Skeeze by count666 May 6, 2004

thoroughbred skeeze 

The single most degrading term for women everywhere. Only the filthiest of strumpets deserve to be called by this disgusting term. This is only suitable for third generation whores.
"Dude Sharyn is such a thoroughbred skeeze she tongue-punched three dudes in the fart-box last night!"
A steak, preferrably a thick juicy one
"Yo man, what's for dinner?"

"A big fat juicy steezy"
steezy by F-Sizzle December 10, 2006