This is a pun of the Cinque de Mayo holiday on May 5. What you get when you eat too much Mexican food, especially with beans.
Watch out, I just made a stinko de mayo. Too much mayonnaise on my wonder bread and baloney sandwich.
by Stinko May 5, 2021

The next day after cinco de mayo when you regret in the bathroom all the spicy food you ate the day before .
by MR.Mister April 25, 2013

by jcustomcue May 7, 2020

Person 1: Do you want any mayo de noche with your fries?
Person 2: Did you take your grandpa's pills again?
Person 2: Did you take your grandpa's pills again?
by Shrek Fan May 5, 2023

by Bear-3 January 6, 2019

An upstate New York term used mainly by Hispanic thug boys or frats to describe a female as being mid or just average quality in looks.
Male 1: Ayo Pablo you see that shorty over there?
Make 2: Yeah homie she a cinco de mayo if I ever saw one
Male 1: you right homes she a middie
Make 2: Yeah homie she a cinco de mayo if I ever saw one
Male 1: you right homes she a middie
by The New York hillbilly February 2, 2023
