Tony: Look at this Green PewDiePie wannabe Jacksepticeye.
Jackson: IKR!
by J03 M4MMA May 1, 2020
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Jacksepticeye is a meme on the Pewdiepie channel.
*saw a ghost* It's Jacksepticeye

We will go down to the hellhole as I like to call it, also Jacksepticeye 's asshole
by LaibaLo February 16, 2018
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Howdy bitch. Jacksepticeye... Your name is not spelledig Sean, its SHAWN
by ig- mramazonas August 14, 2020
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The most annoying mick on YouTube
Parent of a Jacksepticeye fan: Of all the things on YouTube, why did my kid have to be addicted to that annoying asshat Jacksepticeye?
by redgrave1093 October 27, 2019
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as of 2019, an unfunny, uncreative, musty, crusty, sad, cheating excuse for a gaming youtuber.
john: do you watch jacksepticeye?
connor: no, i don’t think he’s funny. i prefer supermega.
by SonicsToes June 30, 2019
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When you yell and scream over everything.
My friend got Jacksepticeye Syndrome after I beat him in a game.
by Theft Tv May 25, 2015
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