DUFF

Designated ugly fat friend

“Trudez is Tims DUFF”
“Luciano will always be a duff”

by Ashkiba February 5, 2018

Duff

That place on the human body (particularly the female body) where the body makes contact when sitting-down, i.e. the erogenous area of the butt.

I'll bet her duff is as sweet as candy!

by anonymous March 3, 2023

DUFF

A DUFF is a D- Dumb U- Ugly F- Fat F- Friend basically the girl or boy that tries to cockblock you when you are trying to make a move on a girl or a boy

Shut up you fuckin duff

by Kiddericc March 22, 2021

Bailey Duff

A weird creature that is ugly and not human

Person 1: the fuck is that
Person 2 : its just a Bailey Duff

by Skkrt skkrt November 3, 2019

elliot duff

An awkward looking man with a wang so small you need a microscope to see it.

Omg his wang was so small! He must be Elliot Duff!

by Jsnsinebusisnssn August 7, 2017

Duff

Designated Ugly Fat Friend is a person that you keep around to be more attractive and popular also known as the D.U.F.F

Two hot girls are sitting with a ugly girl. I feel bad for that Duff.

by Alize Marie September 21, 2017

Duff

Knock someone clean out

Imma duff his dumbass

by Hatehatty6 March 8, 2020