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550 First Avenue

A term used to indicate that someone is unbalanced and/or needs to seek medical attention for a mental disorder.

550 First Avenue is the location of the New York University Department of Psychiatry - one of the largest psychiatry faculties of any department in the United States. Whether the subject is neuropsychiatry or psychoanalysis, psychopharmacology or behavorial therapy, positron emission tomography or epidemiology, child psychiatry or geriatric psychiatry, there is an expert in this field.
Dave: "Did you see John last night - acting all weird? The guy is losing it!"
Bob: "Yep, we'll be sending his Christmas card to 550 First Avenue soon enough."
by Bucko_NZ September 30, 2007
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first mate

The second in command on a ship (I know).

The person most likely to stab the captain in the back, which is ironic as he should be his closest confidant.
Captain Barbosa was second in command as first mate of the Black Pearl before stabbing his captain Jack Sparrow in the back and taking the ship for his own.
by Jamie Douglas December 6, 2006
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Love at first sight

A wonderful thing that almost always ends in heart brake. When you feel a huge attraction for a person with one glance into their eyes.
'hey what do you think of that kid in pe?'
'i think im in love with him'
'you haven't even spoken to him yet'
'have you not heard of love at first sight?'
by gleekgal55 June 21, 2012
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first-year drunk

adjective.
The state of inebriation most commonly attained only by first year students of university
Guy 1: Hey I just finished my exam, whats happening tonight?
Guy 2: Let's go to Koerner's and get first-year drunk!
by seeapeddle October 21, 2010
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first blood

(of DotA)

What you'll hear because
(1) the opponent in your lane is a pro
(2) you are a noob
(3) techies sneaks out from behind

that'll cause you to:
(1) kick the CPU
(2) bang the keyboard
(3) punch the monitor
(4) slap your girlfriend who distracted you
(5) and the least violent method: leave game
leaverpool: techies gone, top and bot care.
<<FIRST BLOOD!!>>
leaverpool: wtf! zzz -.-
by insaneeto May 3, 2006
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Love At First Suck

When a guy and a girl hook up the first time they ever meet and this results in a long term relationship.
(...2 weeks later...)

Dude: Wait, so you guys are going out now?
Boyfriend: Yeah man, her BJ was epic, it was love at first suck
by DEEVSDEVO November 12, 2010
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first niglets

Nickname for Sasha and Malia Obama. See also niglet.
The first niglets are on the Disney channel again.
by abx9500 November 23, 2010
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