Duff

Designated Ugly Fat Friend is a person that you keep around to be more attractive and popular also known as the D.U.F.F

Two hot girls are sitting with a ugly girl. I feel bad for that Duff.

by Alize Marie September 21, 2017

DUFF

Designated Ugly Fat Freind

Jim: Bob you are my designated ugly fat friend (DUFF)
Bob: I'm not that fat!

by z108108 February 18, 2015

Duff Thrust

Simply the coolest move ever to be made by the most awesomest of mascots ever created. Is executed by holding the hip bones with both hands and thrusting the pelvis. But only Duff Man can do a Duff Thrust.
Is used to portray smugness,happiness,or glee or even acknowledgement.

Duffman?!! :O
Oh Yea! *Duff Thrust*

Duff Man,what're you doing?!
Duff Man is Duff Thrusting. Oh yea.

by the one in the closet. August 4, 2010

DUFF

Designated ugly fat friend

“Trudez is Tims DUFF”
“Luciano will always be a duff”

by Ashkiba February 5, 2018

Duff

The shake at the bottom of a bag of drugs, including the seeds and stems in a bag of weed. Commonly used to describe the shake at the bottom of a bag of crystal meth.

Jeff: Hey, let me get a ball of that fire ice. Dan: All I have left is the duff, bro.

by jlthomas110880 November 25, 2020

DUFF

A DUFF is a D- Dumb U- Ugly F- Fat F- Friend basically the girl or boy that tries to cockblock you when you are trying to make a move on a girl or a boy

Shut up you fuckin duff

by Kiddericc March 22, 2021

Bailey Duff

A weird creature that is ugly and not human

Person 1: the fuck is that
Person 2 : its just a Bailey Duff

by Skkrt skkrt November 3, 2019