The retarded sister refers to the non-dominate hand of a male that they don't frequently use for masturbation and does not seem to have the coordination of the dominate hand.
by Ext379 June 24, 2021
Get the Retarded Sistermug. by Kracko January 22, 2011
Get the Slam Sistersmug. 
... is when a guy and a girl are very good friends, and extremely close, spending most of their time together. Eventually, the girl says "I think I love you", or in some way tries to make the relationship a physical one, and the guy simply doesn't feel about her that way, because he "Thinks of her as a sister."
Hence: The Sister Syndrome
Hence: The Sister Syndrome
Girl: Listen, Guy, I think I want to make our relationship between us a romantic one, I want to be more than just friends.
Guy: Ew! Sorry hun, I think we've got a case of Sister Syndrome!
Guy: Ew! Sorry hun, I think we've got a case of Sister Syndrome!
by Russell Bishop May 24, 2007
Get the Sister Syndromemug. A group originally owned by Sister James Charles and has found its way so a small town in Illinois. This squad has a few members because A LOT of the other hoes where fake. IN CONCLUSION a group of bomb ass people that I love <3
by DUmbCunT69 December 9, 2018
Get the SISTER SQUADmug. The best up and coming band of 2004. Set to do great things in 2005. Their album has went to number one many times and was the biggest selling album of the year.
Hits include:
Laura
Take your mama
Mary
Comfortably numb (cover)
Hits include:
Laura
Take your mama
Mary
Comfortably numb (cover)
by Apricot-sunrise January 7, 2005
Get the Scissor Sistersmug. Chet: That girl looks awfully masculine
John: Haha Chet, that isn't a girl, that's a mister sister
Chet: A what?
John: A mister sister. A shemale. A tranny. You gettin' it?
John: Haha Chet, that isn't a girl, that's a mister sister
Chet: A what?
John: A mister sister. A shemale. A tranny. You gettin' it?
by SHMOSEPH May 8, 2013
Get the mister sistermug.