When you have to take a dump right after eating a huge bag of cheetos. Doritos and other orange texturized flavored chips do not count. You should only use the term when the situation is cheetos, not anything else. Spelling doesnt matter as long as its used in the correct context.
After you eat a big bag of cheetos you tell your buddy that youl just be a second, you go the bathroom and realize this might take a while that was a realy big bag of cheetos. For the first time ever youve come to the conclusion you have reached your limit and take a huge dump, the result... an orange duffe.
by od man December 9, 2007

by SauceMilliken July 31, 2017

noun: The small particles of cannabis, or "shake", in the bottom of your bag of weed.
verb: To remove the shake from finished cannabis buds.
verb: To remove the shake from finished cannabis buds.
Noun: "Hey check out this pound of Blue Dream I got!"
Looks at bottom of bag, "I don't know man looks like theres an bunch of duff in it.
Verb: "Gotta duff that shit out bro."
"Have these packs been duffed?"
Looks at bottom of bag, "I don't know man looks like theres an bunch of duff in it.
Verb: "Gotta duff that shit out bro."
"Have these packs been duffed?"
by Little Salt August 7, 2020

by Mikey December 1, 2004

Duff meaning: Dreadful Ugly Fat Freak of a Neighbor.
A neighbor you dread to see out of their house who is ugly on the inside and out. Morbidly obese, fat, and unfortunately seems to scantily clothed most of the time. A loud ass freak who strives to be obnoxious at all times. They tear around the corner and down your street in their reinforced made for fattys' vehicle like a crazy freak, regardless of any pets or kids that may be in the road. You try to live your life but this Duff neighbor makes it virtually impossible to exist within a 3 block radius without hearing their loud ass bi-polar blabbering. This Duff neighbor likes to do the flubby dance while being hit by the jet stream of a water hose which has been known to cause temporary loss of vision for passer-bys.
A neighbor you dread to see out of their house who is ugly on the inside and out. Morbidly obese, fat, and unfortunately seems to scantily clothed most of the time. A loud ass freak who strives to be obnoxious at all times. They tear around the corner and down your street in their reinforced made for fattys' vehicle like a crazy freak, regardless of any pets or kids that may be in the road. You try to live your life but this Duff neighbor makes it virtually impossible to exist within a 3 block radius without hearing their loud ass bi-polar blabbering. This Duff neighbor likes to do the flubby dance while being hit by the jet stream of a water hose which has been known to cause temporary loss of vision for passer-bys.
I thought they had found the house of their dreams until I saw their Duff Neighbor across the street.
The cat never saw that Duff Neighbor coming.
They don't make fences high enough to completely drown out their Duff Neighbor.
The cat never saw that Duff Neighbor coming.
They don't make fences high enough to completely drown out their Duff Neighbor.
by Sass sha J May 29, 2010

by TrexMike March 17, 2021

Two hot chicks at school they usually have a ugly nasty ass friend but this friend is one that their close with . Say a fit boy walks past the duff of the group they only talk to her to get into her pants
by SMITHY March 17, 2015
