1. Reflex exclamation of pain, discomfort or physical shock.

2. (In response to the above) An expression of empathy.

Synonyms: ow, ouch, argh
"Oof, that hurt!"

"Oof, I feel your pain, man!"
by DashW0 May 16, 2010
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(oofinicus sapiens) A species that i basically created and populated an entire country with them.
I am an oof (oofinicus sapiens).
by OOFOOFOOFOOFOOFOOFOOF March 19, 2018
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when you get roasted so hard that you don't now what to say.
mean girl:ur crocs are not even that sparkely
Mean girls friends:YEET
Me:oof jessica I didn't think you'd AtTAcK me like that...oof
by finnayeetis January 14, 2019
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Oof is the Roblox Death Sound, if you play the game you understand what i mean
*Roblox Player Dies*
*Roblox Player Makes the "Oof" Sound
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Retarded Roblox meme that somehow got popular.
Dies in COD*
9-yr-old: oof
by dogwiz November 28, 2017
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Something that one says when hurt, embarrassed,or when they get something wrong.It actually comes from a website called Roblox.Your Avatar says Oof when killed.
*Falls off of bike*OOF
Oof I got an F
Oof I dropped my tray
by TouchMeYouDie March 15, 2018
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