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mad cow disease 

when you piss off a bitch whos over 200lbs
holy shit! that bitches boyfriend wants me and now ive got to deal with mad cow disease
mad cow disease by prettyladyppp February 16, 2009

Mad cow disease 

When a girl lies about her ex/one night stand to her friends to try and embarrass him when her claims are usually 100% bullshit
Girl: you know dat Tyreese?
Friend: the one you hooked up with?
Girl: he got himself a babydick

Tyreese's friend: I hear you got you a babydick
Tyreese: hell no she got that mad cow disease fo sho

Mad cow disease 

Chronic condition whereby twice a day milking just doesn’t cut it. Self milking can occur up to six times especially if the hot cleaner bends over a lot.
This hot weather means pokie nipples and the scent of warm vagina - I got the mad cow disease.

Colorado mad cow

When a girl gives you a hand-job and then slaps you in the face with your own man goo. This is the females revenge for a Colorado snow plow
Dude, I was laying back getting a hand-job and then Stephanie got mad and Colorado mad cowed me.
Colorado mad cow by djjazzyj July 23, 2009

Manitoba mad cow 

The Manitoba Mad Cow is when you pick up a fat chick and while doing her doggy style, you squeeze and twist her titties like you'd milk a cow. Then you ram your dick in her ass without any lube, thus making her mad.
Ex: I hooked up some fat chick with a Manitoba Mad Cow last night, and it was awesome, she was so angry.
Manitoba mad cow by DJ Clamstrong January 16, 2008

Trump 16 Mad Cow Virus 

Any Pro-Trump supporters who use the termTrump Derangement Syndrome to attack anyone who is anti-Trump.
Ruby got called out for having Trump 16 Mad Cow Virus by her friend ,Becky ,after Ruby said that she had Trump Derangement Syndrome .