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Drop out of the gene pool 

A more defined version of "don't breed" and "kill yourself." However, the insult can be interpreted in different ways.
Hank: "Your mother is a whore, Jack."
Jack: "Drop out of the gene pool, Hank."
Related Words

tidy up the garden 

I'm seeing John tomorrow, so I'd better tidy up the garden tonight in advance.

Drown out the Gopher 

The action of pissing in an empty beer bottle and inserting into a females asshole until the bottle is completely empty.
Hillary: I'm feeling a little frisky, I think tonight is the tonight.

Bill: Really? I've been waiting forever to Drown out the gopher.
Drown out the Gopher by GoochTrain November 8, 2016

barbra from the ghetto 

Someone who puts on a blonde weave and a dress and dances to Hairspray songs.

Ex-Good Morning Balitimore, Nicest Kids in Town
Is the flasher that lives next door.
Barbra from the Ghetto just snatched my weave.

Big Deme the Gigolo 

A guy that asks girls out on snap chat and then gets snuck into their house to have sex for $16 a month.
"Big Deme the Gigolo is kind of a big deal"
"I kinda of like hanging out with Big Deme the Gigolo because he looks like a pineapple"

beef is on the grill 

When you have an issue with someone
Can also be used in a question
ex1)I dont understand why Bob stole my prom date, beef is on the grill

ex2) stfu bob no one asked you

beef is on the grill?

YES