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Interstate 494

Interstate 494 is a 43 mile long loop route serving the southern and western areas of the Twin Cities metro area in Minnesota. Its east end is at Interstate 94 in Oakdale and Woodbury, MN. The roadway continues as Interstate 694. The west end of the route is also at 94/694 in Maple Grove.
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Interstate crush

Having feelings, either emotionally or physically, for someone who resides in a separate state from oneself.
I have an interstate crush for someone who lives in Arizona, even though I'm still living in California.
by Dombro October 26, 2009
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Interstate shit distributer

A complete fuckin asshole who drives any new (2015-present) cars. Unarguably the most aggressive drivers on the highway. Most commonly Honda, BMW, Audi, Toyota etc who will chase you down the road, ride your ass for several miles, break check you, and cut your ass off even if you have done nothing. Most commonly in Los Angeles CA and worst of all Phoenix AZ. They are the main cause for most accidents especially if drunk, baked, or tweaked out. Total dickheads.
Good Driver: omg get the fuck off my ass dude *flips bird* and yells YOU FATHERFUCKING INTERSTATE SHIT DISTRIBUTER!!!!!

Interstate shit distributer aggressively around him and either makes a face or swears at him Then gets in front of him and slams the breaks.

Driver 2: YOU ARE ON VIDEO ASSHOLE!!!!
by Jpizzle2110 August 1, 2020
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Interstate Cowboy

A long distance moving truck drivers and crew, who drink, smoke weed, trip, or roll, while on the driving and on the job. Sometimes pejorative.
Those Interstate Cowboys in Truck 101 got busted with weed and coke on their move down in Florida.
by FreakyreD October 13, 2020
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interstate

Person A:Wanna go do 100 on the interstate?
Person B:Sure
*gets on interstate*
Person A: we're going 100 wha- My breaks aren't working

*dies*
by GavinEMC May 7, 2021
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Interstate illness

(Also: highway herpes)

An ailment suffered by those who have spent many hours (or days) in a row traveling the interstate or comparable highway system. Symptoms include persistent headache, grogginess, joint aches and a general fuzziness of the mind.
The two of them were reluctant to talk; interstate illness had properly set in some hours ago and it made conversation hard to focus on.
by NotPieGuy March 20, 2025
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Interstate Autopilot

An honorable sex act that begins with being bored on a road trip, this act usually involves at least two guys. First the passenger must get on top of the driver and begin having Anal sex, while bouncing on top of the driver they must start making out with each other vigorously. After that, due to the drivers riders visual restrictions, the driver must use his tongue to guide the rider how to steer the car. The rider then uses his ass cheeks to turn the steering wheel in whatever direction the drivers tongue pushes in his mouth. This act is preferably to only be done on interstates where the turns are limited.
“Hey I’ve been driving for a while and I’m a little tired, should we put it in interstate autopilot?”
by Autopilotman123 July 27, 2025
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