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Churchhill Down Syndrome 

Closely related to the birth defect Down Syndrome. Which those with the condition have a widely recognized appearance. Churchhill Down Syndrome cause those with the defect to develop horse face. Symptoms vary from person to person and can range from mild to severe. Long face, buggly eyes, and protruding gums and teeth are typical signs of Churchhill Down Syndrome.
Sarah jessica Parker, Celine Dion, and Tori Spelling are examples of celebrities who suffer with Churchhill Down Syndrome.

Post traumatic down syndrome 

Post traumatic down syndrome - a condition that mimicks down syndrome that is directly caused by Trauma.

Maple Syrup Downs' Syndrome Baby 

The spawn of two mentally-handicapped people who engage in passionate sex, then pass out, to wake up and find they have created offspring. In an effort to preserve the baby until a later date upon which they would be more suitable parents, the child is placed into a large beaker full of maple syrup. The babies are then usually apprehended by law enforcement and sold to chinese dining establishments and served as "pork" in House Special Fried Rice.
Holy Shit, my dad told me that I just ate a Maple Syrup Downs' Syndrome Baby!

Upside Down syndrome 

The disorder in which a person's Down syndrome is so severe that his face is completely rotated out of proportion. More severe cases can affect muscle girth, especially in the forearms. This renders the victim's forearms indistingiushable from pencils. One's speech may also become unamusing and trite.
Chris Max, what's up with your face?
Max BABABABAABaabaaba!!!
Chris O, you must have Upside Down syndrome, which renders yours forearms indistingiushable from pencils. My bad.
Upside Down syndrome by max_fisk December 15, 2008

Double Down Syndrome 

The listless state of consciousness experienced after eating a KFC Double Down sandwich.
Brad: "Why does Ken look like he's about to collapse?"

Trevor: "Judging by the lunch we just ate, it is my determination that Ken is suffering from Double Down Syndrome."

Fortnite Down Syndrome 

A person who cannot get off fortnite. If they do they will crave it until they get back on. Some call it Fortnite down syndrome, others call it being 9 years old. What ever It is I have it.
Bro my little brother wont get off fortnite!
Yeah I saw, I think he has Fortnite down syndrome!